SOUNDWAVE MEDICAL

March 14, 2008

New Acoustic Materials Tested, Planned for Future 3VUS Imaging

Right: An engineer checks samples of Acoustic Nanofilm undergoing environmental and acoustic testing.

Ashland, MA: Soundwave Research Laboratories, Inc. announced that it is in early stages of adapting its proprietary Acoustic Nanofilm materials to medical imaging devices. The material, which relies on nanostructured, high strength films configured as an acoustically sensitive surface, has already been commercialized in some of the company's non-medical products. Multiple US and foreign patents are pending on Acoustic Nanofilm, covering carbon nanotube, nanofiber, and nanofilm varieties. The company is currently engaged in licensing and supply discussions with manufacturers of acoustic recording equipment.

"Acoustic Nanofilm is unique" remarked company president Robert Crowley, who has dozens of patents in the acoustics fields, and who is the inventor of the direct view catheter ultrasound system that is still used today to diagnose coronary disease. "The material is incredibly strong, responsive, sensitive, and we think well suited to catheter applications, where size is a constraint".

Soundwave Research Laboratories, Inc. is a developer and manufacturer of sound-sensing products used in recording and medical device industries, and is the owner of 3VUS tm, which is a new 3rd Generation Vascular Ultrasound technology that will be used to obtain clearer images of diseased coronary arteries, so that doctors can perform stent procedures with better results.

November 15, 2007

IVUS Fleet Speeds Development, Shortens Time-to-Market in Medical Devices and 3VUS

Our growing fleet of IVUS consoles now consists of three "research units" that were modified for tissue characterization studies and preservation of the RF envelope, as well as direct digital output. We have two platforms on hand, one being the Boston Scientific research unit which had been at Washington University Medical Center, and two HP Sonos units, both with the very desirable high frequency front ends, capable of up to 100 MHz operation after the filters. HP Medical in Andover knew how to engineer RF front ends the way we prefer, with aggressive noise prevention, and high signal-to-noise ratios maintained. These are not common systems, but they do deliver the best greyscale and sharpest detail of any IVUS console made to date. We have three units that can travel to research and other nonclinical labs and be used support 3VUS and other Intravascular Ultrasound research and development activities. Shown above: A technician performs a bench check on one of the modified Patient Interface Units that works with the modified CVIS console on the right.

March 29, 2007

Soundwave Research Files Further Acoustic Nanofilm TM Patents

Ashland, MA: Medical device manufacturer Soundwave Research Laboratories, Inc. announced today that it has filed additional patent applications covering its proprietary Acoustic Nanofilm TM technology. Soundwave Research Sr. VP Hugh A Tripp made the announcement and described the technology that it covers: "The Acoustic Nanofilm TM technology was invented here at the lab and allows us to convert many polymeric substrates into acoustic and pressure sensitive transducers" he said. "The technology is based on related technology invented by Soundwave Research in the field of nano-enabled sensors and ultrasound transducers, and it can also be applied to non-medical products, such as studio recording microphones".

"This adds to the growing number of patents based on nanotechnology that we are applying to medical imaging, such as 3VUS - Third Generation Vascular Ultrasound - which is an improved form of catheter based coronary imaging needed to see stents and arterial blockages" said CEO Robert J Crowley. "It also allows us to apply the technology early to some non-medical products, work out any manufacturing and quality problems, and be ready for reliable incorporation into medical devices, which have tight quality requirements."

Soundwave Research Laboratories, Inc. is a developer and manufacturer of sound-sensing products used in recording and medical device industries and is the owner of the "Crowley and Tripp" brand of ultra high quality recording microphones that have captured attention and won awards from the recording industry, and consists of 6 released products with several new models pending.

company website http://www.soundwaveresearch.com

January 9, 2007

Vulnerable Plaque, Chronic Total Occlusions, to be focus of Soundwave Medical Transducer Development

Ashland MA January 9, 2007. Soundwave Medical will develop sensors for the detection of vulnerable plaque and for navigating chronic total occlusions, company sources say. Vulnerable plaque is a serious arterial condition that affects a large portion of the population, and can result in sudden cardiac death. Currently there are no ways to detect vulnerable plaque or ways to treat it effectively without highly invasive surgery. The company plans to improve upon an earlier technology developed by founders Robert J Crowley and Hugh A Tripp when they were at then-startup Boston Scientific. "IVUS" which is a catheter based way to look into arterial blockages, is an accepted medical procedure conducted in many catheterization laboratories around the world. Soundwave Medical plans to improve IVUS to make it easier to use, more informative, safer, and more cost effective and sensitive to actual disease states. The company is developing 3VUS tm which is a third generation of the existing technology, but with substantial improvements in performance, cost and manufacturability.

For further information see http://www.soundwaveresearch.com

Acoustic Transducers to use Carbon Nanotubes

Soundwave Medical is developing nanotube array and acoustic nanofilm technologies for use in a wide variety of actuation, sensing, acoustic generation, and sound recording applications.

Shown here is an array of vertical carbon nanotubes on a silicon surface. The use of an array of carbon nanotubes as a charge sensitive capacitor sensor, where a carbon nanotube is responsive to a repelling force, is fundamental to the operation of next generation ultrasound sensors.

September 16, 2006

Soundwave Research Laboratories Spins Out Medical Group

Soundwave Research Laboratories, Inc, a Massachusetts technology firm, announced today that it is forming a new group - Soundwave Medical - to focus on and commercialize certain of the company's proprietary medical technologies relating to imaging and sensing of diseases of the human body.

According to the company, which manufactures a variety of acoustics and audio products under the brand name "Crowley and Tripp", the decision to create a separate business unit is a natural response to company growth. "The mission has always been to develop proprietary technologies in the acoustics field" said company president Robert J Crowley, a technology inventor with over 100 patents and applications to his name, and who started the firm in 2004. "By our second year of operation we established an internationally known brand, developed a dealer network, introduced six new products in the audio field, and grew sales. Our manufacturing capability is growing, and that can now support a more focused and regulated medical device mission" he said.

Soundwave Research Laboratories, Inc., founded in 2004 by ex-Boston Scientific managers Robert J Crowley and Hugh Tripp, has quicky become the quality leader in a type of professional recording microphones known as Ribbon Microphones. "We are fortunate that professional audio product technologies have been like a warm up, a way to assemble the structure of the company so that all aspects of R&D, intellectual property development, manufacturing, and internal systems are in place to support more rigorous medical manufacturing requirements" remarked co-founder Hugh Tripp, who spent 20 plus years with industry leaders such as Acoustic Research and Boston Scientific and developed several basic medical technologies used today.

Spinoff Soundwave Medical will first focus on ultrasound devices, such as transducers that have also been applied to their microphones, according to the company. At least one ultrasound system has already been built and shipped to a cancer research center, says the company, and further ultrasound work will include a new type of catheter that looks into hearts and is codenamed "3VUS". Other medical device activities have been ongoing, according to Crowley, who has an optimistic view of what's ahead: "I think we've done well to establish ourselves. That's good, but we have to grow, and that means being squarely in high value fields such as cardiology, where the demand for new and better medical technologies is strong".

August 30, 2006